穿琥宁与复方丹参注射液合用治疗小儿轮状病毒肠炎

Observation of curativee ffect on 106 cases of infant rotavirus enteritis with andrographolide added compound tanshinane injection

目的:观察穿琥宁和复方丹参注射液联合治疗小儿轮状病毒肠炎的临床疗效。方法:208例患儿随机分为对照组102例,常规给予利巴韦林治疗。治疗组106例给予穿琥宁15～20mg/(kg.d)和复方丹参注射液1ml/(kg.d)治疗。结果:对照组总有效率84.3%,治疗组总有效率94.3%,有显著差异(χ2=5.52,P<0.05);住院时间对照组4.58±1.16d,治疗组3.98±1.02d,两组有显著性差异(t=3.95,P<0.01),结论:穿琥宁和复方丹参注射液联合治疗小儿轮状病毒肠炎有良好疗效。

犦Objective:Toobserveclinicaleffectsofandrographolideaddedcompoundtanshinaneinjectiontoinfantrotavirusenteritispa-tients.Method:208Casesofinfantrotavirusenteritispatientsweredividedrandomlyintothecontrolgrouptreatedwithribavirinasusual,andthetreatgroupof106casestreatedwithandrographolide15～20mg/(kg.d)addedcompoundtanshinaneinjection1ml/(kg.d).Result:Thetotaleffcctiverateofthecontrolgroupis84.3%,whiletherateorthetreatgrouptotalis94.3%.Thedifferenceisremarkable(χ2=5.52,P<0.05).Thecourseoftherapyforthetreatgroupisshorterthanthatofthecontrolgroup.Thereissignificantdiffferenbetweentwogroup(t=3.95,P<0.01).Conclusion:Andrographolideaddedcompoundtanshinaneinjectionisaneffectivemedicineintreatmentofinfantrotavirusenteritis.犤