低分子量肝素在肾病综合征中的临床应用

Low molecular weight heparin in the treatment of nephrotic syndrome

目的 观察低分子量肝素对原发性肾病综合征的治疗作用。方法 将诊断为原发性肾病综合征的 3 2例患者随机分为对照组和观察组 ,对照组予激素标准疗法 ,观察组在对照组用药的基础上加用低分子量肝素 (LMWH )。结果 观察组在降低尿蛋白、血胆固醇、血液粘滞度及升高血清白蛋白方面明显优于对照组。结论 低分子量肝素对原发性肾病综合征有明显的肾脏保护作用。

Objective To observe the therapeutic effectiveness of low molecular weight heparin (LMWH) in the treatment of primary nephrotic syndrome. Methods 32 patients diagnosed with primary nephrotic syndrome were randomly divided into the control group and the observed group. The control group were given standard therapy with hormone, and the observed group received the same basic treatment as that in the control group plus LMWH. Results In decreasing the urinary protein, blood cholesterol, blood viscosity and in increasing serum albumin, the therapeutic effectiveness in the observed group was better than that in the control group. Conclusions LMWH could protect the primary nephrotic syndrome.