1Fihn SD, Callahan CM, Martin DC, et al: The risk for and severity of bleeding complications in elderly patients treated with warfarin. The National Consortium of Aconsorrium of Antieoagulation Clinics. Ann Intern Med 1996;124:970-979.
2Stroke Prevention in Atrial Fibrillation II Investigators: Warfarin versus aspirin for prevention of thrombocembolism is artial fibrillation: Stroke Prevention in Atrial Fibrillation II Study. Lancet 1994;343:687-391.
3Landefeld CS, Goldman L: Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy. Am J Med 1989; 87: 144-152.
4Petitti DB, Strom BL, Melmon KL: Prothrombin time ratio and other factors associated with bleeding in patinets treated with warfarin. J Clin Epidemiol 1989;42:759-764.
5vander Meer FJ, Rosendaal FR, Vandebroucke JP, et al: Bleeding complications in oral anticoagulant therapy. An analysis of risk factors. Arch Intern Med 1993;153: 1557-1562.
6Lauabjerg J, Egeblad H, Heaf J, et al: Bleeding complications to oral anticoagulant therapy: multivariate analysis of 1010 treatment years in 551 outpatients. J INtern Med 1991; 229: 351-355.
7Beyth RJ, Landefeld CS: Anticoaguants in older patients. A safety perspective. Drugs Aging 1995; 6: 45-54.
8Stroke Prevetion in Atrial Fibrillation Investigators: Bleeding during antithrombotic therapy in patients with atrial fibrillation. The Stroke Prevention in Atrial Fibrillation Investigators. Arch Intern Med 199; 156: 409-416.
9Hylek EM, Skates SJ, Sheehan MA, et al: An analysis of the lowest effective intensity of prophylactic anticoagulation for patients with nonrheumatic atrial fibrillation, N Engi J Med 1996; 335: 540-546.
10Stroke Prevention in Atrial Fibrillation III Investigators: Adjusteddose warfarin vernus low-intensity, Fixed-dose warfarin plus aspirin for hightrisk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised Clinical trial. Lancet 1996; 348: 633-638.