摘要
目的 探讨改善严重蛛网膜下腔出血临床症状的方法。方法 ①选择蛛网膜下腔出血Hunt’分级Ⅲ级以上的病例 ,并对出血情况进行CT分级。②对所选择的病例试用大剂量甲基强的松龙治疗 ,并按比例逐渐减量 ,整个疗程为 7d。③治疗开始后密切观察病人的临床表现。结果 治疗 11例病人 ,平均用药后 4～ 5d即可见病人的临床症状及体征得到改善 ,与对照组比较有显著差异 ,并且未发现有明显的药物副反应。结论 初步应用大剂量甲基强的松龙治疗严重蛛网膜下腔出血的病人 ,具有起效快、疗效好、无明显毒副作用等特点。
Objective To explore the pharmacological method to improve clinical manifestation of the patients with severe subarachnoid hemorrhage.Methods ①The cases of SAH with larger than the 3rd grade in Hunt's Classification were selected for the study.②All cases selected were divided into two groups(11 cases of treated group with high dose methylprednisolone , its dose would be decreased gradually, and whole course of treatment lasted for 7 days; 13 cases of controlled group).③During the treatment,the patient's symptom and sign were recorded carefully.Results Treated group had obvious improvement of symptom and sign within 4～5 days after administration.Compared with controlled group,treated group was significantly different( P <0 05) and the side-effect had not been observed during the treatment Conclusion As a preliminary treatment of the patients with severe SAH,high dose methylprednisolone showed a rapid and high effect and no complication.
出处
《中国急救医学》
CAS
CSCD
北大核心
2002年第2期95-96,共2页
Chinese Journal of Critical Care Medicine
关键词
蛛网膜下腔出血
甲基强的松龙
临床表现
Subarachnoid hemorrhage
Methylprednisolone
Clinical manifestation
