福建水华微囊藻的急性毒性及肝脏损伤作用

Toxic Effects of Microcystis Aeruginosa Water-Blooms from a Reseroir in Fujian

目的 鉴定福建省某水库中水华微囊藻的毒性。 方法 采集某水库水华微囊藻 ,采用昆明鼠腹腔注射法测试其毒性。 结果 该水华微囊藻具有肝毒性 ,主要中毒症状是引起实验动物肝脏瘀血肿大 ,其 Lmin为 2 0 .7g藻浆 / kg体重 ,L D50 为 9.9g藻浆 / kg体重 ,染毒小鼠死亡时间为2～ 2 .5 h。 结论 福建省某水库中水华微囊藻具有致死性肝毒素 。

Objective To identify the toxic effects of algal water blooms from a reservoirin. Fujian Methods Algal cells of microcystis aeruginosa were collected from a reseroir in Fujian. The raw toxin was extracted by the method of Harada and the toxicities was tested by mice bioassay.Results The extracts from lyophilized algal cells posed hepatotoxicity by intraperitoneal injection. The animal liver weights increased and the liver was congested with blood.The LD 50 is 9 9g algae paste/kg of mice. Conclusion The microcystis aeruginosa water blooms were toxic.