紫外分光光度法测定麻黄素洗必泰滴鼻液的含量

Determination of Ephedrine and Chlorhexidine Nasal Drops by UV Spectrophotometry

目的 建立麻黄素洗必泰滴鼻液中盐酸麻黄碱和醋酸洗必泰的含量测定方法。方法 采用双波长分光光度法消除组分间干扰进行含量测定。结果 方法的线性关系良好 ,盐酸麻黄碱平均回收率为 10 1.0 % ,RSD=0 .75 % (n=5 ) ,醋酸洗必泰平均回收率为 10 0 .6% ,RSD=0 .42 %(n=5 )。 结论 本法简便、快速、准确。

OBJECTIVE To develop a method for determining the contents of ephedrine hydrochloride and chlorhexidine acetate in nasal drops.METHODS The dual wavelength spectrophotometric method was used for eliminating mutual interference.RESULTS The method was linear and reproducible.The average recovery was 101 0%,RSD 0 75%(n=5),for ephedrine hydrochloride and 100 6%, RSD=0 42%(n=5),for chlorhexidine acetate.CONCLUSION The method was simple,rapid and accurate.