灼口综合征患者口腔念珠菌生物类型初探

Identification of oral Candida spieces in patients with burning mouth syndrome

目的 :了解灼口综合征 (burningmouthsyndrome ,BMS)患者口腔念珠菌的生物类型。 方法 :采取漱口法对BMS患者和对照进行了口腔念珠菌的检测和API念珠菌生物类型鉴定。结果 :BMS组的念珠菌检出率与对照组相比无统计学差异 ;第一型BMS的念珠菌检出率为 2 8.1% ,经危险度估计念珠菌检出阳性有发生第一型BMS的危险 ;两组受试者所分离的念珠菌均以白色念珠菌为主。结论 :BMS组和对照组所分离的念珠菌均以白色念珠菌为主。念珠菌在第一型BMS的发生中 ,可能具有一定的作用。

砄bjective: To investigate the role of Candida species in burning mouth syndrome (BMS) in a Chinese cohort. Methods: The studied population comprised 52 BMS patients and 37 healthy controls. An oral rinse technique was used to detect the candidal carriage. The isolates were identified using API 20C AUX Candida identification kit.Results: Candida was found in 3 out of 37 of the controls(8.1%) and in 10 out of 52 BMS patients(19.2%). 25 strains of Candida were isolated from the 10 Candida positive BMS cases, 22 out of the 25 strains were Candida albicans while 3 were Candida prarapsilosis . 7 strains of Candida were isolated from the 3 Candida positive controls and all the 7 were Candida albicans . Conclusion: Candida infection may play a role in the development of BMS, especially in the type 1 subtype.