雷公藤茎、叶对免疫功能的影响

Effect of the Stem and Leaf of Tripterygium wilfordii on Immune Function

目的:研究雷公藤茎、叶水提取物对机体免疫功能的影响。方法:采用灌胃给药,观察雷公藤茎、叶对小鼠碳粒廓清、免疫器官、血清溶血素含量及迟发性超敏反应的影响。结果:雷公藤茎、叶均具有降低小鼠碳粒廓清指数、脾脏指数、胸腺指数和血清溶血素含量,抑制迟发性超敏反应的作用。结论:雷公藤茎、叶对机体非特异性免疫、体液免疫及细胞免疫均具抑制作用。

Objective:To study the effect of water extracts from the stem and leaf of Tripterygium wilforaii Hook. f. on Hook. f. immune function. Methods:The effect of the stem and leaf of Trpterygium wilfordii on the clearance of charcoal particles,the index of thymus gland and spleen,the level of serum hemolysin and the delayed hypersensitivity were observed in mice by ig. Results:The stem and leaf of Tripterygium wilfordi could decrease the clearance of charcoal particles,the index of thymus gland and spleen,the level of serum hemolysin and inhibit the delayed hypersensitivity in mice. Conclusions:The stem and leaf of Tripterygium wilfordii could inhibit nonspecific,humeral and cellular immunity.