青钱柳多糖降血糖作用研究

Study on Reducing Blood Sugar of Polysaccharide from Cyclocarya paliurus(Batal.) Djinsk

目的:探讨胡桃科植物青钱柳中是否含有具有降血糖作用的多糖复合物。方法:采用超声波萃取法提取多糖成分。用四氧嘧啶糖尿病小鼠模型验证青钱柳多糖的生物活性。结果:青钱柳中多糖复合物含量为9.6％。灌胃青钱柳多糖四周后,小鼠血糖值比糖尿病模型组降低了41.3％。给予小鼠葡萄糖后,青钱柳多糖组小鼠血糖值显著低于糖尿病模型组。结论:青钱柳中含有多糖复合物。这种复合物具有显著的降血糖活性并能增强糖尿病小鼠对葡萄糖的耐受力。

Objective:To try to find Cyclocarya paliurus (Batal.) Iljinsk contains the polysaccharide complex with reducing blood-sugar activity or not. Method:The Polysaccharide was extracted by ultrasonic wave. The diabetes model was induced by alloxan to verify the activity of the polysaccharide. Results:The content of the polgsccharide is 9.6 % in Cyclocarya paliurus. The blood- sugar level of the polysaccharide group is lower by 41.3 % than that of the diabetes model group. After ig glucose,the blood-sugar level of the pollysaccharide group was obviously lower than that of the diabetes model group. Conclusion:Cyclocarya paliurus ( Batal.) Djinsk is rich in polysaccharide complex,which have obvious reducing blood-sugar activity and can improve the capability of glucose tolerance in diabetes mice.