颅骨肿瘤119例临床分析

Tumor of the skull-report on 119 patients

目的 探讨颅骨肿瘤的常见病理类型、临床特点和治疗方法。方法 回顾性分析 119例手术治疗的颅骨肿瘤病例 ,对其临床症状、影像学资料、治疗方法以及生存情况等进行分析研究。结果 共行神经外科手术 12 2次 ,3人行手术 2次。全切除手术 75次 ,近全切除手术 2 4次 ,部分切除手术 2 2次 ,1例患者行活检手术。外生型肿瘤 43例 (36 .1% ) ,内生型肿瘤 2 7例 (2 2 .7% ) ,混合生长型肿瘤 49例 (4 1.2 % )。随诊 85例患者中 ,78.6 %的患者术后恢复了正常的工作和学习 ,16 .6 %的患者术后生活可以自理 ,生活需要照顾以及随访期间死亡的患者各 2例。结论 积极的手术治疗可以达到明确诊断 ,延缓神经功能缺损的发展 ,延长患者的生存期以及美容等目的。

Objective To study the pathologic type, clinical manifestations and treatment of skull neoplasms. Methods A series of 119 patients with skull neoplasm were analyzed retrospectively with respect of clinical manifestations, radiologic features, treatment and prognosis. Results 122 operations were done with 3 patients being operated twice. Complete resection was done 75 times, subtotal resection 24 times, partial resection 22 times and biopsy only once. Gross type: exophytic 43(36.1%), endophytic 27(22.7%) and mixed type 49(41.2%). Among the 85 patients followed, 78.6% have recovered and are living well, 16.6% of patients are self-caring, 2 need others' help and 2 have died. Conclusion Most skull neoplasms require neurosurgical intervention. Surgical excision is able to confirm the diagnosis, slow down the progression of neurologic dysfunction, prolong the patients' lives and improve the cosmetic results.