CA19-9的检测对胰腺癌早期诊断及术后预后判断的临床意义

The Clinical Significance of CA19-9 in Early Diagnosis and Postoperative Prognosis of Patients with Pancreatic Carcinoma

目的 探讨CA 19 9的检测对胰腺癌早期诊断及术后预后判断的临床意义。方法 采用放射免疫法动态检测胰腺癌患者术后CA 19 9水平 ,以判断其与肿瘤局部复发或远处转移的关系。结果 早期胰腺癌患者CA19 9值为 (85 .3± 6.7)U /ml ,慢性胰腺炎患者为 (15 .7± 1.9)U /ml ,两者比较有显著性差异 ;胰腺癌患者术后CA 19 9水平均降至正常 ,但术后动态检测发现 ,CA19 9升高者提示有局部复发或远处转移 ,3个月后影像学 (CT )检查才发现变化。结论 CA19 9的检测可作为胰腺癌早期诊断及术后判断预后的

Objective To investigate the clinical significance of CA19 9 in early diagnosis and postoperative prognosis of patients with pancreatic carcinoma.Methods CA19 9 level in patients with pancreatic carcinoma of early state was compared with that in chronic pancreatisis,and was determined sequentially in patients with pancreatic carcinoma after tumor resection.Results CA19 9 value in patients with pancreatic carcinoma of early state was(85.3±6.7)U/ml,and in patients with chronic pancreatisis it was(15.7±1.9)U/ml,there was significantly difference between them.The postoperative value of CA19 9 returned to normal in all cases after tumor resection.The elevation of CA19 9 value suggested recurrence or metastasis,and the changes in CT was observed after three months later.Conclusion CA19 9 may be an important mark in diagnosis and postoperative determination of patients with pancreatic carcinoma.