阿司匹林对冠心病患者C反应蛋白的影响

The Effect of Aspirin on C-reactive Protein in Patients with Coronary Heart Disease

为研究阿司匹林对冠心病患者 C反应蛋白的影响及了解 C反应蛋白 ( CRP)与冠心病 ( CHD)的关系。我们观察 86例 CHD患者 ,3 2例正常对照者的 CRP浓度改变 ;以及应用不同剂量的阿司匹林 8周后 CHD患者 CRP浓度的影响。结果显示 CHD患者的 CRP浓度较正常对照组增高 ( P<0 .0 5 ) ,不同剂量的阿司匹林对 CHD患者的 CRP浓度改变不一样 ;阿司匹林 15 0 mg/ d剂量 ,疗程 8周可降低 CHD患者的 CRP浓度 ( P<0 .0 5 )。提示中、长期应用非小剂量的阿司匹林可降低 CHD患者的

Objective To study on the effect of aspirin on C-reactive protein in patients with coronary heart disease(CHD). CRP concentrations were examined in 86 patients with CHD, another 32 normal subjects as controls. The effect of different dosages of aspirin on CRP concentrations. CRP concentration in patients with coronary artery disease was significantly higher than that of the normal subjects(P<0 05). CRP concentration in patients with CHD could be reduced with aspirin 150 mg/d for 8 weeks(P<0 05). This study suggests that CRP concentration on patients with CHD could be reduced with bigger dosage of aspirin.