强直性脊椎炎并发前葡萄膜炎35例报告

Ankylosing spondylitis and anterior uveitis of 35 cases

目的 探讨强直性脊椎炎 (AS)与前葡萄膜炎的关系及可能的意义。方法 对资料完整的 3 5例强直性脊椎炎并发前葡萄膜炎病人的临床特点、HLA B2 7及放射学检查进行分析。结果 3 5例AS并发的前葡萄膜炎全部为急性前葡萄膜炎 (AAU) ,其中 2 5例HLA B2 7阳性 ,占 71% ,放射学检查均显示轻重不等的骶髂关节炎性改变。结论 强直性脊椎炎与前葡萄膜炎关系密切 ,对原因不明的前葡萄膜炎病人进行HLA B2 7及放射学检查有助于早期发现AS。

Objective To investgate the realationship on anterior uveitis with ankylosing spondylitis(AS) and its clinical implication.Methods 35 cases of AS accompany anterior uveitis were analyzed by its clinical feature,HLA B 27 antigen and radiological examination.Results All the patients appeared acute anterior uveitis(AAU),there were 25 cases of HLA B 27 positive,and radiological examination showed sacroilitis in all patients.Conclusion Anterior uveitis and AS are associatied closely.HLA B 27 and radiological examination are helpful in early diagnosis of AS in patients with anterior uveitis for which the causes are unknown.