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端粒酶与细胞周期调控 被引量:3

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摘要 端粒的缩短和端粒酶的激活在细胞衰老和永生化过程中的作用已被证实并受到广泛关注。许多酶和蛋白参与细胞周期调控 ,其中以G1/S期转换关卡的调控最为重要。细胞染色体的稳定主要取决于端粒长度和细胞周期转移关卡之间的相互作用 ,而肿瘤细胞端粒长度的维持大部分情况下与端粒酶活性表达有关。端粒酶与细胞周期调控因子之间关系的研究将为我们探索肿瘤病因及新的肿瘤治疗途径开辟广阔的前景。
作者 陈琰 杨连甲
出处 《陕西肿瘤医学》 2002年第1期72-74,共3页 ShanXi Oncology Medicine
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参考文献25

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