1997～2000年浙江省钩端螺旋体病监测分析

Surveillance and Problem Analysis of Leptospirosis in Zhejiang Province from 1997 to 2000

目的 探讨钩端螺旋体病(钩体病)流行规律,分析存在问题。方法 用MAT法检测病人、水鸭和蛙血清抗体;同时分离培养病原体。用夹夜法捕鼠,采集鼠肾、猪肾、牛中段尿、蛙肾、水鸭肾和蚂蝗血分离培养病原体。结果 1997～2000年全省共发生钩体病789例,平均发病率为0.44/10万,死亡12人,平均病死率为1.52％。衢州、丽水和台州市的发病数占全省发病总数的93.28％。病例主要分布在7～10月,占95.06％。病人血清抗体阳性率为65.43％,菌群主要为黄疸出血群和七日热群。病人血培养阳性率为1.20％。鼠密度为5.08％,以黑线姬鼠为优势种,占47.34％。鼠带菌率为6.90％,黑线姬鼠带菌率为13.19％。蛙肾阳性率为0.17％。水鸭血清抗体阳性率为50％,菌株主要为秋季群;蛙血抗体阳性率为13.64％,菌株为秋季群。结论 钩体病防制工作不能放松,要加强对该病的监测和防治工作。

Objective To grasp the surveillance of Leptospirosis in Zhejiang province, and analyse its problem. Methods Use MAT to test the serum antibody in patients, ducks and frogs. Culture the Leptospira with the serum of patients, ducks, frogs and pig's kidney, frog's kidney, duck's kidney, cattle's urine, mouse's kidney. Results From 1997 to 2000 the total patients of Leptospirosis in whole province are 789. The average incidence is 0.44 per 100 000, 12 of them were die. Most of patients are in Quzhou, Lishui and Taizhou city. The positive rate of serum antibody in patients and frogs, ducks are 65.43% , 13.64% and 50%, respectively. The culture positive rate of patient's blood, mouse's kidney , frog's kidney are 1.20 percent ,6.90 percent and 0.17 percent, respectively. Conclusions The provention and control of Leptospirosis can not relax, surveillance should be enhanced.