摘要
目的 :研究冠状动脉 (冠脉 )内支架术后冠脉血流储备的变化。 方法 :18例冠脉造影示单支病变进行支架术的患者测定支架术前后的冠脉血流储备 ,并以术后血流储备 2 5为界将患者分为 2组 (恢复组 :7例 ,支架术后冠脉血流储备 >2 5 ,异常组 :11例 ,支架术后冠脉血流储备≤ 2 5 ) ,比较 2组冠脉血流储备的变化及一般情况。 结果 :恢复组和异常组 2组术后较术前血流储备均明显增高 (恢复组 :2 2± 0 6和 3 1± 0 3 ,P <0 0 5 ;异常组 :1 3± 0 4和 1 9± 0 4,P <0 0 5 )。与恢复组比较异常组中心肌梗死患者明显增多 (7/11和 1/7,P <0 0 5 ) ,高血压者明显增多 (9/11和 2 /7,P <0 0 5 )且冠脉狭窄程度严重〔(84± 4) %和 (65± 9) % ,P <0 0 0 1〕。 结论 :支架术后即刻冠脉血流储备改善 ,其程度与心肌梗死、高血压及狭窄严重性有关。
Objective:To evaluate the coronary flow reserve(CFR)immediately after stent implantation. Methods:CFR was measured in 18 patients with 1 vessel disease and normal left ventricular function before and after stent implantation using a Doppler wire distal to the stenosis.Hemodynamic and angiographic measurements were recorded before and immediately after stenting. Results:CFR was>2 5 after stenting in 7 patients (recovery group)and≤2 5 in 11(abnormal group).In both groups,CFR was statistically increased after stent implantation(2 2±0 6 and 3 1±0 3,p<0 05;1 3±0 4 and 1 9±0 4,p<0 05).More myocardial infarction(7/11 vs. 1/7,p<0 05),hypertension(9/11 vs. 2/7,p<0 05)and more severe coronary stenosis were found in the abnormal group than in the recovery group〔(84±4)% vs.(65±9)%,p<0 001〕. Conclusion:After coronary stenting CFR can be improved immediately.The improvement is correlated with the severity of myocardial infarction,hypertension and coronary stenosis.
出处
《中国循环杂志》
CSCD
北大核心
2002年第1期35-37,共3页
Chinese Circulation Journal