不同游泳时间对高脂饮食老年大鼠血浆脂蛋白、载脂蛋白的影响

Swimming training and the changes of serum lipids, lipoproteins and apolipoproteins in rats with fed-caused hyperlipoproteinemia

目的 :观察不同强度游泳运动对老年高脂饮食大鼠血脂、脂蛋白和载脂蛋白的影响 ,从而了解不同强度运动对动脉粥样硬化的预防作用。方法 :15月龄、雄性SD大鼠在饲喂高脂饮食的同时进行长、短两种不同时间的游泳 ,持续 15周。结果 :大鼠进食 15周高脂膳食后形成了高胆固醇血症模型 ;运动使大鼠血浆HDL -C、ApoAI明显升高 (P <0 .0 1,P <0 .0 5 ) ,TG显著下降 (P <0 .0 5 ) ;低运动强度可刺激ApoAI增高 ,比大运动强度对改善血脂代谢紊乱更有效。结论

Objective:In order to understand the effects of prevention of the different intensities for atherosclerosis , the changes of serum lipids, lipoproteins and apolipoproteins after swimming training for 15 weeks in rats were observed. Method: SD rats, male, 15 month years old, was randomly assigned to swimming training with 45min or 90min per day, which lasted 15 weeks. Training progressed with the high-fat feed at the same time. Result:Hypercholesterolemia in high-fat fed rats was established after 15 weeks; The serum HDL-C, ApoAI were significantly increased( P <0.01, P <0.05) and TG markedly decreased( P <0.05) in rats with intervention of exercise; low intensity exercise was better than higher intensity for improving the lipoprotein disorder through stimulating the increase of ApoAI in rats. Conclusion:Low intensity exercise has better effects on prevention of atherosclerosis for fed-caused hyperlipoproteinemia in rats.