川崎病患儿血清中多种病毒抗体IgM的检测

Detection of various virus antibody IgM levels of the serum in the acute phase of KD

目的 :了解川崎病与病毒感染的关系。方法 :采用ELISA法检测川崎病患儿急性期血清多种病毒抗体IgM。结果 :96例川崎病患儿血清抗CVB病毒抗体阳性率为 4 2 86 % ,关联强度OR =6 .75 ,95 %可信区间 (CI)为 3.14～ 14 5 2 ,明显高于抗其他病毒IgM抗体阳性率 ;川崎病患儿抗CVBIgM抗体阳性率也明显高于同期住院的非感染组抗CVBIgM抗体阳性率 10 % (X2=7.0 6 ,P <0 0 0 0 1)。结论

Objective: To understand the relationship between the onset of KD and virus infection. Methods: The serum levels of various virus antibody IgM were detected by ELISA in the acute phase of KD. Results: Positive rate of the serum antibody CVB in 96 cases with KD was 42.86%,which was significantly higher than that of other virus OR=6.75,95% confidence interval(CI)3.14-14.52] and it was significantly higher than that of control group(X2=7.06,P<0.0001).Conclusion: there may be significant association between the onset of KD and CVB infection. and it was significantly higher than that of control group(X2=7.06,P<0.0001).Conclusion: there may be significant association between the onset of KD and CVB infection.