肾综合征出血热并发神经系统损伤的原因分析

The causes of nervous system damage in hemorrhagic fever with renal syndrome

目的 进一步增强对肾综合征出血热 (HFRS)并发神经系统损伤的原因及控制诱因的认识。方法 分析2 4例HFRS患者出现神经系统损伤的原因以及治疗措施所起的作用。结果 神经系统损伤的主要原因包括 :低钠性脑病、高渗性昏迷、高氮质血症、高血容量致脑水肿及病毒直接损伤等。结论 HFRS并发神经系统损伤的原因较复杂 ,病死率高 ;加强对原发病的治疗、及时除去有关诱发因素可降低神经系统损伤的发生率 ,从而提高重型。

Objective To study the causes of nervous system damage in hemorrhagic fever with renal syndrome and how to control. Methods The causes of nervous system damage in 24 patients with HFRS were analyzed and the role of therapeutics was evaluated. Results The main causes of nervous system damage included hyponatrium encephalopathy, hyperosmolar nonketotic diabetic coma, hyperazotemia, encephaledema caused by hypervolemia, direct damage of virus and so on. Conclusion The causes of nervous system damage in HFRS are very complicated and there is a high fatality rate in these patients. The incidence of nervous system damage would be decreased by strengthening the treatment of the primary affection and eliminating the evoking factors. Thus, the cure rate of serious HFRS will be raised.