单项绒毛膜促性腺激素值在辅助生殖技术中预测妊娠结局的临床意义

The clinical implication of serum β-human chorionic gonadotropin in predicting the outcome of pregnancy with assisted reproductive technology.

目的 探讨辅助生殖技术中单项血 β绒毛膜促性腺激素 ( β HCG)值预测妊娠结局的临床意义。 方法 对采用辅助生殖技术治疗受孕的不孕症患者的临床资料进行分析。定时监测血 β HCG水平 ,并追踪妊娠结局。 结果 血 β HCG水平与妊娠结局明显相关 ,β HCG <10 0mIU/L者75 .0 %有不良妊娠结局 ,而 β HCG >10 0mIU/L ,则94 .7%的患者妊娠超过12周。结论 辅助生殖技术中 β HCG值是一项有意义的预测妊娠结局的指标。

Objective To investigate the clinical implication of serum β-human chorionic gonadotropin (β-HCG) in predicting the outcome of pregnancy with assisted reproductive technology (ART).Methods The clinical data of infertile women in ART pregnancies were analyzed.The serum β-HCG was monitored regularly, and the pregnancy outcome was followed up.Results The levels of β-HCG showed a clearly correlation with outcome of ART pregnancies.The low levels of β-HCG(<100 mIU/L) were associated with a probability of the poor pregnant outcome ( 75.0%), whereas levels of β-HCG (>100 mIU/L) could predict a 94.7% chance of gestational age>12 weeks.Conclusion Serum β-HCG level 16 days after ovulation is a useful predictor for pregnant outcome.