益康宁口服液对小鼠免疫功能的影响

Effect of Yikangning on immunological function in mice

目的 :探讨益康宁口服液 (YOL)对小鼠免疫功能的影响。方法 :用 X线照射和环磷酰胺 (Cy)制备小鼠免疫抑制模型 ,采用同位素掺入法 ,分别检测用药后小鼠脾细胞转化率 ;通过病理切片 ,光学显微镜下观察 YOL对辐射所造成的小鼠免疫器官损伤的保护作用。结果 :YOL能拮抗辐射所造成的小鼠免疫器官损伤 ,提高小鼠 T、B淋巴细胞对亚适量 Con A和 L PS刺激的转化率 ,能使免疫抑制小鼠脾细胞自发转化率及 Con A和 LPS刺激的转化率明显升高 ,使降低的免疫功能恢复正常。结论 :YOL能保护小鼠免疫器官 。

Objective:To investigate the effect of Yikangning oral liquid on immunological function in mice.Methods: 3H TdR incorporation was used to detect the lymphocyte transformation rate for Con A and LPS. Results :The drug increased the lymphocyte transformation rate in mice with lowed immunological function. Conclusion :Yikangning enhances immunological function in mice with lowered immunological function.