动脉留管介入治疗晚期胰腺癌的临床体会

Clinical experiences of interventional treatment for advanced pancreatic carcinoma through implanting arterial catheter

目的 :探讨晚期胰腺癌导管介入治疗疗效。方法 :采用 Seldinger技术将导管选入腹腔干动脉及肠系膜上动脉造影 ,明确肿瘤供血动脉以留置导管。术后连续 3d微量泵灌注化疗药物 ,共治疗14例。结果 :介入治疗后 ,疼痛消失或明显缓解 ,血液生化指标明显改善 ,影像学上肿块缩小 ,患者生存期延长。结论 :晚期胰腺癌患者经导管区域性化疗疗效好 ,毒副作用小 ,是一种值得临床上推广的疗法。

Objective: To study the efficacy of interventional therapy in advanced pancreatic carcinomas. Methods: By applying Seldinger's technique, a catheter was implanted into truncus coeliacus and mesenterica superior artery, and the catheter was located at tumor′s main supplying vessel. After operation, chemotherapeutic drugs were perfused continuously through micro-artery pump for three days in 14 patients. Results: After interventional treatment, there was marked relief or disappearance of pain and significant improvement of lab results,and mass in image reduced and survival time prolonged. Conclusion: Regional chemotherapy through catheter is effective for advanced pancreatic carcinomas and there were less toxic side effects. It is worth popularizing in clinical treatmentatment,there was marked relie