黛力新治疗抑郁性神经症的听觉事件相关电位分析

Auditory event-related Potential Analysis of Deanxit Treatment of Depressive Neurosis

目的 :通过电生理检测 ,评估黛力新对抑郁性神经症的疗效。方法 :比较 5 0例抑郁性神经症在黛力新治疗前后的 P30 0 测量数值 ,并根据抑郁的临床相分成轻度和中度二组。用配对 t检验比较治疗前后 P30 0 成份变化。结果 :中度抑郁临床相组治疗后比治疗前 P30 0 波幅增高 (P<0 .0 5 ) ,潜伏期、反应时间较治疗前缩短 (P<0 .0 5 )。轻度抑郁临床相组治疗后比治疗前 P30 0 波幅增高 ,潜伏期缩短 ,但无统计学差异。结论 :P30 0

Objective:To evaluate the deanxit cutative effect on the treatment of depressive neurosis through electrical physiological test.Method:Compare the P 300 testing digits of 50 depression sufferers with those before the deanxit treatment,and divide these 50 patients into a slight and a medium group auording to their clinical manifestations,then use paired to check P 300 component changes against those before the treatment.Result:In the group with medium clinical manifestations,P 300 amplitude is higher,both the incmbatim period and response time become shorter in comparison with those before the treatment.(P<0.05) while in test group with slight clinical manifestation,P 300 amplitude is higher, the incubation period also becomes shorter than that before the treatment,yet they show no statistical difference.Conclusion:P 300 test can be an index in the observation of curatine effect on the deanxit treatment of depressive neurosis with medium clinical manifestation.