异丙酚静脉全麻对初孕与经产妇人工流产效果比较

A comparison of result of intravenous anesthesia with propofol in suction termination of pregancy in parturients and multiparas

目的 异丙酚静脉全麻对初孕与经产妇人工流产效果的比较。方法 ASAⅠ～Ⅱ级孕妇 10 0例 ,孕期 6～ 8周 ,初孕妇与经产妇各 5 0例。异丙酚 2～ 3mg·kg-1静脉全麻行人工流产。比较两组术前、术中、术后血压 (BP)血氧饱和度 (SpO2 ) ,心率 (HR)的变化 ,记录用药剂量、手术时间、清醒时间及副作用。结果 两组BP、SpO2 、HR变化无差异。初孕组异丙酚平均剂量为 (195 30± 40 )mg ,经产妇组平均剂量为 (12 0 2 5± 30 )mg。手术时间初孕组 (5 5 4± 2 14)min ,经产妇组 (4 4± 1 2 5 )min。清醒时间初孕组 (6 5± 1 2 )min ,经产妇组 (5 6± 2 3)min。初孕妇组术后发生呕吐及清醒前轻度燥动各 2例。经产妇组未发生呕吐。结论 异丙酚用于人工流产 ,初孕组的剂量明显大于经产妇组 。

Objective To compare of effect of intravenous anesthesia with propofol in suction termination of pregancy in parturients and multiparas. Methods 100 ASAⅠ～Ⅱpregant women in 6～8 weeks were divided into two groups (50 parturients and 50 multiparas). Dosage of propofol 2～3 mg/kg was used to intravenous anesthesia in suction termination of pregancy. Systemic blood pressure (SBP),diastolic blood pressure (DBP), heart rate (HR) and pulse oxygen saturation (SpO 2) were measured respectively during operation. Dosage of propofol, average surgical time, recovery time and side effect were observed. Results There were no differences in SBP, DBP, HR, SpO 2 between two groups .The average dose of propofol in parturients and multiparas were (195.30±40)mg, (120.25±30)mg respectively. The average of surgical time in parturients and multiparas were (5.54±2.14) min,(4.4±1.25) min respectively. Recovery time in parturients were (6.5±1.2) min, the others were (5.6±2.3) min. Vomiting and slight restlessness before recovery in parturients were two cases respectively , but no vomiting in multiparas. Conclusion Dosage of propofol in parturients are significantly more than in multiparas, recovery time in parturients is more than in multiparas with propofol anesthesia.