尿液分泌型IgA对鉴别上、下尿路感染临床意义的研究

Urinary secretory immunoglobulin a(sIgA) measurements clinical value in discriminating the site of urinary tract infection

目的 :测定尿液中sIgA以鉴别上、下尿路感染。方法 :建立ELISA法测定尿液中sIgA。结果 :肾盂肾炎病人尿液sIgA浓度明显高于膀胱炎和正常对照组。膀胱炎和正常对照组比较无明显差异。结论 :测定尿液sIgA可用于确定尿路感染部位 ,可做为一个诊断指标。

Objective To assay urinary sIgA fevel and discriminate the upper and lower urinary tract infection.Method Establish ELISA for sIgA,to assay urinary sIgA.Results The urinary sIgA levels in pyelonephritis patients was significantly higher than that in normal and cystitis groups,The urinary sIgA levels in the normal and cystitis groups were equivalent.Conclusion The measurment of sIgA in urine may be used to determine the site of urinary tract infection.And we believe that it may act as index of diagnosis.