复方升白胶囊的质量标准研究

Studies on the quality control of fufangshengbai capsules

目的 :建立复方升白胶囊的质量检测方法。方法 :用薄层色谱法对该胶囊剂中的枸杞子、女贞子和当归进行了鉴别 ;用高效液相色谱法测定该胶囊剂中芍药苷 (Paeoniflorin)的含量。结果 :薄层色谱中斑点清晰 ,易于识别 ;芍药苷进样量在0 1987～ 0 9936 μg内呈线性关系 ,r=0 9995 ,平均加样回收率为 98 8% ,RSD为 1 9%。结论

Objective:To establish a method for quality control of Fufangshengbai capsules.Methods:The Fructus lycii,Fructus ligustri lucidi and Radix angelicae sinensis were identifide by TLC.The content of paeoniflorin in this capsule was determined by HPLC.Results:The spots in the TLC were clear and were well distinguished well.The linear range was 0 198～0 9936μg(r=0 995).The average recovery was 98 8%,and the RSD was 1 9%.Conclusion:This method can be used for quality control of Fufangshengbai capsules.