1Kuiper G,Enmark E,Pelto-Huikko M,et al. Cloning of a novel estrogen receptor expression in rat prostate and ovary. Proc Natl Acad Sci USA 1996;93:5925
2Enmark E,Pelto-Huikko M,Grandien K,et al. Human estrogen receptor β-gene structure, chromosomal lacolization, and expression pattem. J Clin Endocrinol Metab 1997;82:4258
3Gray TK. 13 β-esdtradiol acts directly on the clonal osteonlast cell line UMR 160.Proc Natl Acad Sci USA 1987;84:6267
4Komm BS. Estrogen binding receptor mRNA and biologic response in osteoblast-like osteosarcoma cells. Science 1988;241:81
5Ernst M; Heath JK; Rodan GA. Estradiol effects on proliferation of mRNA for collagen and IGF- 1, and PTH stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones. Endocrinology 1989; 125(2): 825
6Merry JO, Oursler. Modulation of transforming TGF-β production on normal human osteoblast-like cells by 17-β estrodiol and parathyroid hormone. Endocrinology 1991; 129:3313
7Hofbauer LG, Khosla S, Dunstan CR, et al. Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology 1999; 140(9) :4367
9Girasole G, 17-β estradiol-inhibits interleukin-6 production by bone marrowderived stromal cells and osteoblasts in vitro; a potential mechanism for the antiosteoporotic effect of estrogens. J Clin Invest 1992;89:883
10Pacifici R, Brown C, Puscheck E, et al. The effects of surgical menopause and estrogen replacement on cytokine release from human blood monocytes. Proc Netl Acad Sci USA 1991; 88:5134
6Lindsay R, Gallagher JC, Kleerekoper Ⅲ, et al. Effect of lower doses of lower doses of conjugated equine estrogens with and without medroxyprogesterone acetate on bone in early postmenopausal women[J ]. JAMA, 2002,287(20) : 2668 - 2676.
7Vidal O, Kindblom LG, Lhlsson C, et al. Expression and localization of estrogen receptor-βin murine and human bone [J]. J Bone Mineral Res, 1999, 14(6):923-929.
8Gray, Flymn TC, Gray KM, et al. 17 - βestradiol acts directly on the clonal osteoblastic cell line UMR106[J]. Pro Natl Acad Sci, 1987, 87: 6267-6271.
9Komm BS,Terpening CM, Benz DJ, et al. Estrogen binding, receptor mRNA, and biologic response in osteoblast - like osteosarcoma cells[J]. Science, 1988,241:81 - 3.
10Khosla S, Melton LJ 3rd, Atkinson EJ, et al. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women, a key role for bioavailable estrogen[J]. J Clin Endocrinol Metab, 1998, 83: 2266 - 2268.