原发性心肌病猝死(附12例法医病理分析)

Pathological Analysis on Sudden Unexpected Death in 12 Cases of Primary Cardiomyopathy

本文对原发性心肌病猝死12例进行了病理分析。其中肥厚型心肌病6例,扩张型心肌病2例,心内膜弹性纤维增生症4例。肥厚型:室间隔明显增厚,镜检可见排列紊乱、形态奇特的心肌纤维和明显的纤维化病变,间质中的小动脉平滑肌肥厚,内膜增厚;扩张型:病变与肥厚型类似;心内膜弹性纤维增生症:其中1例活到49岁,较为罕见,其病理改变除各室腔内膜明显弹性纤维与胶原纤维增生外,心肌间质中小动脉内膜也具有同样病变。

Pathological analysis of twelve cases of Primary cardiomyopathy has been made.of them 6cases are of hypertrophic type.2 are of dilated type and 4 are with endocardioal fibroelastosis. The hypertrophic type is characterized by hypertrophy of Ventricular septum,bizarre arrengment of various sized muscle fibers and severe fi- brosis and other changes including prominert proliforetion of hypertrop- hied smooth muscle cells and marked endo-fibroelactosis of small coron- ary arteries.The pathological changes of 2cases of dilated type is similar to that seen in the hypertrophic type.The one of 4 cases of endocardical fibroelactosis amony whom has unexpectedly survived for 49 years.The pathological changs in interstitial small arteries are similar to these wh- ich hadbeen seen in the endo-cardium.