4-(N-乙基,N-2-羟乙基)氨基苯甲醛的制备

Preparation of 4-[N-Ethyl,N-(hydroxyethyl)]aminobenzaldehyde

以 4 - (N -乙基 ,N - 2 -羟乙基 )氨基苯为起始原料经乙酸酐酯化 ,苯环对位甲酰化 ,再水解制得 4 - (N -乙基 ,N -2 -羟乙基 )氨基苯甲醛。每步反应平稳 ,并用TLC跟踪每一步反应进行的程度。总收率达 6 0 %

N-ethyl,N-hydroxyethy)aminobenzaldehyde was synthesized using 4-(N-Ethyl,N-hydroxyethyl)amino benzene as starting material.Every step of reaction,for example esterification,formylation and hydrolysis run smoothly and was monitored with TLC.The over-all yield reached 60%.