硒催化的邻硝基苯胺类化合物的羰基化反应

Selenium-catalyzed Carbonyllation of ortho-Nitroaniline and its Derivatives

用硒作催化剂 ,三乙胺为助催化剂 ,CO为羰基化试剂 ,通过氧化还原羰基化的方法 ,将邻硝基苯胺类化合物在分子内羰基化成环 ,反应生成相应的一系列环脲类物质。此催化合成方法的反应选择性近乎 1 0 0 % ,收率较高 ,操作简单 。

o Nitroaniline and its derivatives may produce a series of cyclic ureas by applying the method of selenium catalyzed CO oxidative and reductive carbonylation. The selectivity of this reaction is very good and the yields of products are relatively high. It′s easy to operate. The possible mechanism of this reaction is proposed.