氨基酸卟啉锌配合物对氨基酸酯的分子识别

Molecular Recognition of Amino Acid Esters by Amino Acid Modified Porphyrinatozinc (Ⅱ)

本文用紫外 可见吸收光谱滴定方法研究了一种新型的苏氨酸卟啉锌配合物 (主体分子 )对氨基酸酯 (客体分子 )的分子识别。这种锌卟啉可以与氨基酸酯形成 1∶1和 1∶2的两种加合物。客体分子的氨基首先与主体分子上氨基酸残基的羧基作用形成 1∶1的加合物 ,然后另一客体分子的氨基与锌卟啉的中央锌原子配位形成 1∶2的加合物。客体分子与主体分子上的氨基酸残基之间的库仑力作用以及主

The molecular recognition of a new kind of threonine modified porphyrinatozinc (Ⅱ) (host) to amino acid esters (guest) has been detected with UV Vis absorption spectrum titration method. This porphyrinatozinc (Ⅱ) forms 1∶1 and 1∶2 adducts with amino acid esters. At first, the amino group of amino acid esters interacts with the carboxyl group of the amino acid residue of this porphyrinatozinc (Ⅱ) to form 1∶1 adducts. Then, the amino group of amino acid esters coordinates with the central zinc atom of this porphyrinatozinc (Ⅱ) to form 1∶2 adducts. The Coulomb interaction and the London's dispersion forces between the host and the guest may be the other two kinds of interactions that make this porphyrinatozinc (Ⅱ) recognize amino acid esters.