亚低温治疗重度颅脑损伤的疗效分析

Analysis of clinical curative effect on patients with severe brain injury

目的 :探讨亚低温治疗对重度颅脑损伤的临床疗效。方法 :对 1999年 1月～ 2 0 0 0年 6月收治的 5 8例重型颅脑损伤患者在常规治疗的基础上采用亚低温治疗 ,作为治疗组。随机抽取 1995年 7月～ 1997年 7月期间常规治疗的 5 8例重型颅脑损伤患者 ,作为对照组 ,与之比较。并对两组中的原发性脑干损伤的患者的疗效进行对比分析。结果 :两组在颅内压、体温、心率、血糖、死亡率等指标方面有显著差异。结论 :亚低温能降低重型颅脑损伤患者的死亡率 ,降低颅内压 ,抑制伤后早期高血糖 ,对原发性脑干损伤有明显的治疗效果 ,可提高生存率。

Objective:To investigate clinical effect of mild hypothemia on patients with severe brain injury.Methods:The hypothermic group were made up of 58 patients with severe brain injury from 1999,1 to 2000,6 and the control group were consisted of 58 patients with severe brain injury who was randomly abstracted from 1995,7 to 1997,7.The former were treated with hypothermia in addition to conventional treatment and the other were administered to routine treatment.Contrast analysis were performed between the two groups and the prognosis of the patients with primary Brain Stem injury during the two groups were evaluated respectively.Results:There were significant difference between mild hypothermal group and control group on intracranial pressure (ICP),blood glucose,heart rate,the death rate,the cure rate and so on.Conclusions:Mild hypothermia can reduce the mortality,decline ICp,inhibit high glucose during the prime period of severe head injury.It can acquire obvious curative effects on patients with primary brain stern injury and increase the cure rate.