低分子肝素钠治疗不稳定型心绞痛临床观察

Effectiveness of low molecular weight heparin for the treatment of unstable angina pectoris.

目的 观察低分子肝素钠治疗不稳定型心绞痛 ( UA)临床疗效。方法 将 76例 U A患者随机分为常规治疗组 (对照组 )及常规治疗加低分子肝素钠组 (治疗组 ) ,疗程为 10天。结果 10天总有效率 :治疗组为 94 .73 % ,对照组为76.3 2 % ( P<0 .0 5 ) ;观察 8周治疗组无 1例发生 AMI,对照组 2例 ( 5 .2 6% )发生 AMI。结论 在常规治疗基础上加用低分子肝素钠 ,能有效控制心绞痛发作 。

Objective To observe the clinical therapeutic effectiveness of low molecular weight heparin for the treatment of unstable angina pectoris.Methods Seventy six cases of unstable angina pectoris were randomly allocated into the routinely treated group(control group)and routine treatment combined with low molecular weight heparin group(treatment group).The therapeutic course was 10 days.Results The rate of effectiveness was 94.73% in the treatment group and 76.32% in the control group at the end of the therapeutic course( P <0 05).After 8 weeksobservation,no acute myocardial infarction (AMI) happened in the treatment group,but 2 cases of AMI took place in the control group(5.26%).There was no obvious adverse reaction seen in the treatment group.Conclusion Low molecular weight heparin combined with routine treatment can control angina pectoris and decrease the incidence of myocardial infarction more effectively.