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凋亡抑制蛋白与临床疾病 被引量:2

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摘要 近年新发现一类凋亡抑制蛋白(inhibitor of apoptosis family of protein, IAPs),广泛存在于许多物种如病毒、真核生物、哺乳动物中。IAP家族分子高度同源,功能上具有抑制细胞凋亡的作用,与肿瘤、神经元变性、脑缺血等疾病的发生发展有关,故了解IAP的生物学特征,认识其在凋亡调控中的作用机制及与维持机体正常生理功能之间的关系,对恶性肿瘤、神经细胞死亡的治疗具有重要的理论和实残意义。
作者 李晓南
出处 《国外医学(儿科学分册)》 2002年第1期15-17,共3页 Foreign Medical Sciences(Section of Pediatrics)
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参考文献17

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同被引文献13

  • 1杨丹,韩立敏.1969-2003年子宫内膜癌发病率及发病因素分析[J].复旦学报(医学版),2005,32(4):479-480. 被引量:33
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