肺心病患者体内TNF、TXB2、PGFla变化及临床意义

The clinic value and change of plasma TNF, TXB_2 and PGFIa in patients with chronic pulmonary heart disease

目的探讨慢性肺源性心脏病 (简称肺心病 )体内肿瘤坏死因子 (TNF) ,血栓素 β2(TXB2 ) ,6 酮 前列腺素 (PGFla)的变化和临床意义。方法分别抽取肺心病急性加重期及缓解期晨起空腹血 ,用GD 40 0 a计数器 ,通过放免法测定血浆中TNF ,TXB2 及PGFla的含量。结果治疗后TNF、TXB2 降低 ,PGFla升高。结论肺心病体内TNF、TXB2 、PGFla含量变化 ,可作为判断病情严重程度的实验指标。

Objective To evaluate the clinical value and change of plasma TNF, TXB 2 and PGFIa in patients with chronic pulmonary heart disease (CPHD). Methods The plasma TNF TXB 2 and PGFIa were measured with DG-400-a calculator by radioimmunoassary in the cases during acure and revive CPHD . Results The plasma TNF and TXB 2 decreased PGFIa increased after the cases with CPHD were relieved. Conclusion The change of the plasma TNF, TXB 2 and PGFIa in CPHD can be judged how extent the cases are senous.