摘要
目的 :采用记忆合金腔内支架治疗严重气管狭窄 ,并观察长期置入体内支架的生物相容性。方法 :记忆合金支架在变形后 ,用自制的双腔气囊导管置入气管内。定期行纤维内窥镜及影像学检查 ,并对置入气管内 2个月、10个月、14个月后脱落取出的支架表面进行了电镜观察及年腐蚀率测定。结果 :全部 10例患者在支架置入后 ,呼吸困难均立即缓解 ,良性疾病者长期携带支架效果满意。长期置入体内的支架 ,记忆特性没有任何改变。合金的年腐蚀率测定结果远小于Ⅰ级的指标 (3× 10 - 3mm year)。 结论 :对于不能手术切除的严重气管狭窄的患者 ,记忆合金腔内支架能起到减症治疗的目的。长期置入体内的支架仍显示良好的生物相容性。
Objective:To treat inoperable severe tracheal stenosis by using nitinol endotracheal stent and to study the biocompatibility of which being long term implanted in the body Methods: The stent was deformed to smaller size in iced water With a self made introducer, the stent was placed in the location of stenosis After hot water was injected into the introducer, the stent resumed its original form and anchored there Items such as roentgenography, endoscopy were performed By means of electronic microscope and micro balance, corrosion situation on the surface of stents were studied after long term implantation(2,10,14months) Results: Altogether 10 patients with severe tracheal stenosis received this treatment Dyspnea was relieved immediately after implantation of stents in all patients Long term follow up also showed satisfactory results The stent has a good biocompatibility after long term implantation in the body Conclusions: Nitinol stent as a new endoprosthesis is effective in treatment of inoperable severe tracheal stenosis It has some remarkable advantages as compared with other tracheal stents
出处
《军医进修学院学报》
CAS
2002年第1期35-37,共3页
Academic Journal of Pla Postgraduate Medical School
基金
"十五"军队科研基金项目 (0 1Q0 5 7)