动脉灌注化疗药物和免疫制剂在治疗晚期胃肠道肿瘤中的应用

CLINICAL STUDY ON THE EFFECT OF INTRA-ARTERIAL INFUSION CHEMOTHERAPEUTIC MEDICINE AND IMMUNIZATOR OF LATER GASTRO-INTESTINAL CARCINOMA

为评价动脉内灌注化疗药物和免疫制剂对治疗晚期胃肠道肿瘤的临床疗效 ,将 86例不能切除的胃肠道肿瘤随机分成两组 ,A组 4 6例 ,行动脉灌注化疗同时进行免疫治疗 ,B组 4 0例 ,单纯动脉灌注化疗。结果肿瘤治疗有效率 (CR +PR)A组 82 6 % ,B组5 2 5 % ;0 5、1和 2年生存率 ,A组分别为 10 0 %、82 6 %和 5 6 5 % ,B组分别为 10 0 %、6 5 %和 4 2 5 %。

To evaluate the effect of intra arterial infusion chemotherapeutic medicine and immunizator in treatment of later gastro intestinal carcinoma, 86 cases suffering from irremovable gastro intestinal carcinoma were divided into treatment group(group A) and control group (group B). 46 cases in group A were treated with intra arterial chemo immunotherapy, 40 cases in group B were treated only with chemotherapy. Effective rates of group A and group B were 82 6% and 52 5% ( P <0 01) .The survival rate of 0 5, 1 and 2 years in group A was 100%, 82 6%, 56 5%, and in group B was 100%, 65%, 42 5%. Intra arterial infusion chemotherapeutic medicine and immunizator can increase the therapeutic effect of later gastro intestinal carcinoma .