脐静脉血浆胃动素浓度测定及其意义

Plasma Motilin Concentration in Cord Venous Blood

本文测定了４５例足月正常新生儿脐静脉血浆胃动素浓度，并与４５例正常产妇进行比较，结果表明脐静脉血浆平均胃动素浓度为３９６．００±８５．５０ｎｇ／Ｌ，与产妇血浆平均胃动素浓度（３９３．５３±５５．０３ｎｇ／Ｌ）基本相等（Ｐ＞０．０５），但明显高于正常育龄非孕妇女（３６１．１２±９６．２３ｎｇ／Ｌ），Ｐ＜０．０１；不同性别的新生儿，其胃动素浓度无明显差异（Ｐ＞０．０５）。提示新生儿脐静脉血胃动素浓度较高，其意义可能有助于新生儿胃肠道结构和功能的进一步发育和成熟。

Plasma motilin concentrations were measured by radioimmuno-assay in cord venous blood from 45 healthy term neonates,and compared with that of postpartum women. Resuls showed that plasma motilin concentration is similar in neonated(396.00+85.50 ng/L) and postpartum women(393.53±55.03ng/L)P>0.05;and ooth these levels were significantly higher than that of healthy nonpregnant women(361.12±96.23ng/L) P<0.01;there was no significantly di-fference in cord venous blood motilin levels both sexes. Our finding suggests that there was higher concentration of motilin and that this could play an important role in the structure and growth of the gastrointestinal tract for adaptations to extruterine nutrition.