甲硝唑药棒治疗牙周病的疗效评价

Clinical Observation of the Therapeutic Effect on Periodontal Diseases with Metronidazole Strip

报告用甲硝唑药棒治疗牙周病的临床疗效。将门诊病人随机分为治疗组(79个牙)和对照组(21个牙)。结果:经治疗1～8天后,治疗组总有效率为100％,对照组14.3％。经秩和检验,两组之间差异有非常显著意义(H=42.25,P<0.005)。治疗组又分为洁治组(29个牙)和非洁治组,(50个牙),统计学无差异。甲硝唑在牙周袋中缓慢释出药物,作用持久,达到消炎、止痛、止血、抗菌斑作用,未见有副作用。

The therapeutic effects of metronidazole strip on periodontal disease have been reported. The patients were divided into treated group (79 teeth) and control group (21 teeth) at random. The results showed that the total efficient rate was 100% in the treated group compared with that of 14.3% in control group after 1-8 days of treatment. There was significant difference between the two groups (H=42.25,P<0. 005). The treated group was further divided into scaling group (29 teeth )and no scaling group (50 teeth ) and no difference was found between the two groups. The metronidazole strip released drugs gradually and remained effective in the periodontal pocket for a considerable period of time to be functional in anti-inflammatory, analgesic, hemostatic and anti-plaque effects. No toxic and side effects of the drug strip was encountered.