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14例大疱性表皮坏死松解型药疹治疗体会

Treatment of 14 Patients with Epidermolysis Bullosa Drug Eruption
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摘要 报告14例大疱性表皮坏死松解型药疹的治疗。以磺胺类药和解热镇痛药引起者居多,各4例。皮损面积按九分法计算:皮损面积80%以上者9例,80%以下者5例,治愈9例,死亡5例,我们认为早期使用足够剂量皮质激素类药物是有效措施。病程中注意防治感染,给予足够的液体以防止水电解质失平衡,局部治疗使用本院制中药“五黄油”。 Treatment of tourteen patients with epidermolusis bullosa drug erupion has been reported. The major causes were sulfonamides and antipyretic analegesics,each of which involved 4 patients. According to the 'The rule of nines' method used in burn patient to evaluate the cutaneous lesion,over 80% of the surface area in 9 patients and under 80% in 5 patients were encountered. Among the 14 patients, 9 were cured and 5 died. The results suggest that emphasis should be placed on early treatment by enough dosage of cortical hormone ,control of infection ,enogh fluid transfusion to keep the patients from water-electrolyte unbalance and local application of Chinese traditional herb pharmaceutics'Wu Huang You'.
作者 王惠中 郑庸
出处 《江西医学院学报》 1991年第4期60-62,共3页 Acta Academiae Medicinae Jiangxi
关键词 药物疗法 大疱性表皮松解症 病因学 磺胺类 镇痛药 药物副作用 epidermolysis bullosa/drug therapy epidermolysis bullosa/etiology sulfonamides/adverse effects analgesics. anti-inflammatory/adverse effects
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