血清唾液酸对血液病临床价值的初步报告

Clinical Evaluation of Serum Sialic Acid in Hematopathy——A Pretiminary Study

报道64例各类血液病患者血清唾液酸(SA)值的测定,并与84例健康对照组进行比较,结果经统计学分析:病例组(631.5±130.3μg/ml)与对照组(522.0±61.4 μg/ml),病例组中的ANLL(672.6±98.38 μg/ml)、ALL(630.8+129.3 μg/ml),CML—A(617.5±122.7μg/ml),MM(606.0138.7μg/ml 四组与对照组比较,差异有极显著意义(P<0.01);各病型组 SA 阳性率明显高于健康对照组,表明 SA 值的测定对恶性血液病的诊断有一定的临床意义。

Sialic acid(SA)in the secum of sixty four patients with various kinds of hematopathy was detect- ed,analysed statisticelly and Compared with that of 84 healthy controls.The results showed 631.5± 130.31 μg/ml in the patients group and 522.0±61.4 μg/ml in me health controls.They were 672.6±98.38 μg/ml in patients with ANLL,630.8±129.3 μg/ml in ALL,617.5±122.7μg/ml in CML—A and 606.0±138.7 μg/ml in MM.There was significant difference between the patients and the healthy controls(P<0.01).The positive rate of SA in various types of blood diseases was much higher than that in controls.This study suggests that SA content bears certain Clinical significance in the diagnosis of malignant hematologic diseases.