饮用水NO_3^-污染与食管癌发病率及死亡率相关性探讨——以河南省林州安阳地区为例

STUDY OF CORRELATION FOR THE NO_3^- CONTAMINATION OF DRINKING WATER AND FOR THE RATE OF DISEASE AND DEATH OF ESOPHAGUS CANCER OF LINZHOU AND ANYANG IN HENAN PROVINCE

阐明了林州市食管癌流行的 4个特征。根据 46个饮用水的 NO-3 分析资料 ,论证亚硝胺的前体物 NO-3 的分布与食管癌的地理分布具有明显的相关性 :林州市的发病率是北部高于南部 ;林州市—安阳县—范县的发病率是西部大于东部。居民饮用NO-3 超标的浅层地下水、旱井水是导致食管癌的重要原因之一。 70年代以来 ,大量施用化肥是引起饮用地下水 NO-3 污染的根本原因 ,它导致的后果是林州市食管癌发病率和死亡率下降缓慢。指出了必须坚持“防霉、去胺、施钼肥、治增生、改变不良饮食习惯”五项预防措施 。

The discussion of the four characteristics of esophagus cancer in Linzhou reveals that the geographical distribution of NO - 3 and esophagus cancer can be obviously correlated from analytical data for drinking water NO - 3 of 46 samples.It is found that northern Linzhou has a high NO - 3 content in drinking water than its southern part and that western Linzhou Anyang Fanxian is larger than the eastern part.The excessive content of NO - 3 in drinking water is one of the important causes of esophagus cancer.Since 70's,the excessive utilization of chemical fertilizer has caused the contamination of NO - 3 in drinking water.Therefore,the rate of disease and death of esophagus cancer in Linzhou is slowly decreased.We propose that five measures must be taken:prevent the mildew,move the amine,use the fertilizer of molybdenum,treat the hyperplasia,change the bad habit of drinking and eating,particularly manage the drinking water.