急性心肌梗死溶栓治疗对心脏舒张功能的影响

The effect of cardiac diastolic function in acute myocardial infarction with intravenous thrombolysis

目的 :观察急性心肌梗死 (AMI)患者静脉溶栓治疗对心脏舒张功能的影响。方法 :选择接受静脉溶栓治疗的AMI患者 5 0例 ,用HP2 5 0 0彩色多普勒超声心动图测定二尖瓣血流A峰 /E峰面积 (VA/VE)、左室射血分数 (LVEF)、短轴缩短率 (FS) ,以及应用Killip分级判定心功能。 结果 :36例溶通组与 14例未通组相比 ,VA/VE比值明显低于未通组( 1 0 12 9± 0 342 7比 1 3335± 0 40 77,P <0 0 1) ;VA/VE >1出现率少 ( 4 7 2 %比 85 7% ,P <0 0 5 )。结论 :静脉溶栓治疗AMI使梗死相关血管再灌注后 。

Objective To investigate the effect of cardiac diastolic function in the patients with acute myocardiac infarction(AMI) receiving intravenous thrombolysis administration Methods 50 patients with AMI receiving intravenous thrombolysis were studied.VA/VE LVEF,FS were measured by HP 2500 Color Doppler Echocardiography and the cardiac function of the patients was assessed by Killip grade.Results VA/VE of the group of fibrinolysis (36 cases)compared with no fibrinolysis(14 cases) was significantly decerased(1.0129±0.342 vs 0.3335±0.4077,P<0.01),and VA/VE>1 rarely occured in fibrinolysis group (47.2% vs 85.7% ,P<0.05).Conclusion AMI with introvenous thrombolysis following ischemic reperfusion plays a great role in left ventricular cardiac diastolic function.