乙肝病毒携带者肿瘤标志物的变化与肝癌发病关系的探讨

Study on the relationship of tumor marker of hepatitiis B virus carrier and liver cancer

目的 观察乙肝病毒携带者肿瘤标志物变化与肝癌发病的关系。方法 将乙肝病毒携带者 6 0例随机分为两组 ,试验组 30例用抗病毒与保肝法治疗 ,对照组不用药物。检测每个病人肿瘤标志物 (AFP、AFU、γ -GT、CEA)的变化。结果 试验组中AFP、AFU、γ -GT、CEA四种肿瘤标志物浓度明显下降 ,而对照组无变化。在此基础上对 80 0 0例HBV携带者的癌变情况进行观察 ,经过 3年的随访研究 ,发现治疗组癌变率明显低于对照组。

Objective?To observe the relationship of tumor marker of hepatitis B virus carrier and liver cancer.Methods?Sixty patients were randomly divided into two groups,thirty cases in the treatment group were treated with medicine and 30 cases in the control group without treatment.Every patient was checked in tumor marker including AFP,AFU,γ-GT and CEA.Results?AFP,AFU,γ-GT and CEA decreased clearly in the treatment group and no change in the control group.On the basis we also observe 8000 cases HBV-B carriers.Afler three years canceration rate of the treatment group is lower than that of the control group.Conclusion?We may reduce tumor marker to prevent the hepatitis B transfering to hepatoma.