全身毛发受累的念珠形发1例

Generalized monilethrix: A case report

报告1例21岁男性患者,自幼头发稀少,头部营养不良性秃发,全身毛发程度不一的串珠状改变或黑点状断发,伴毛囊角化性丘疹。光镜见典型串珠状改变。扫描电镜观察胸毛,一根毛小皮消失,一根存在,狭窄部见明显的纵嵴,纵沟。病理见毛囊稀少、萎缩。

A case of generalized monilethrix was reported. A 21 year old male patient presented dystrophic alopecia, variable beaded hair or black spotted broken hair with follicular keratosis all over the body. SEM of two chest hairs showed the absence of cuticle in one of the two examined . Longitudinal ridges and ditches were noted on the surface, especially on the narrow internodes. Histopathology of scalp showed sparse follicles, atrophic follicles without hair.