三黄泻心汤传统饮片汤剂与中药配方颗粒汤剂药效比较

Pharmacodynamic Comparison between Sanhuang Decoction for Purging Stomach-fire and Its Concentrated Granule

目的:探讨中药配方颗粒汤剂替代传统饮片汤剂的可能性。方法:对比研究了三黄泻心汤传统饮片汤剂与中药配方颗粒汤剂对二甲苯致小鼠耳廓肿胀、对小鼠断尾止血以及对小鼠小肠运动的影响。结果:除中、高剂量组对小鼠小肠运动的影响有差异外,其余指标两种汤剂低、中、高剂量组间均无显著性差异。结论:经典方的中药配方颗粒汤剂具研究、开发意义。

Objective: To discuss the feasibility that a traditional decoction is substitued by its concentraed gratnule. Methods: The effects of the two kinds of decoction were compared on mice auricle tumefaction induced by xylene, arresting bleeding of mice broken tails and mice alvine creepage. Result: There was no remarkable difference between two kinds of decoction on pharmacodynamic effects except purging action. Conclusion: The research and exploitation of classical prescription concentrated granule has great signifaction.