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不同剂量依那普利逆转高血压患者蛋白尿的研究

The Study of Effect of Enalaprilat at Difference Dose on Regressing Albluninuria in Patients with Hypertension
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摘要 目的:研究不同剂量依那普利逆转高血压患者蛋白尿的情况。方法:将126例高血压合并蛋白尿患者分为A、B、C3个组分别每天给予10mg、20mg和40mg依那普利,6个月后比较各组蛋白尿的转阴率。结果:B、C组蛋白尿的转阴率明显高于A组。但B和C组比较无显著性差异。结论:每天给予20mg依那普利可能是逆转高血压蛋白尿较合理的剂量。 To study effect of Enalapriiat at difference dose on regressing albuminuria in patients with hypertension. Methods: 126 hyper-tensive patients wilh Albuminuria were divided into three groups A,B and C and administrated 10mg,20mg,40mg Enalapriiat daily respectively. After six months, negative rale of albuminuria were compared among groups. Results: Negative rate of albuminuria in groups B and C was significantly higher than in group A,but no difference between group B and C.Conclusion: 10mg may be a seasonable dose for Enalapriiat regressing albuminuria in hyper-tensive patients.
出处 《医学理论与实践》 2002年第3期266-267,共2页 The Journal of Medical Theory and Practice
关键词 高血压 蛋白尿 依那普利 治疗 Hypertension, Albuminuria,Enalaprilat
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参考文献4

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  • 2[2]Chan JC, Ko GT, Leung DH, et al. Long-term effects of angiotensin-converting en zyme inhibitor and metabolic control in hypertensive type 2 diabetic patients. Kidney Int 2000;57(2) :590 ~ 600
  • 3[3]Cooper ME, Renal protection and angiotesin converting enzyme inhibition in microalbuminuric type Ⅰ and Ⅱ diabetic patients J Hypertens Suppl 1996; 14(6): S1 1 ~ 4
  • 4[4]Roossing P, Tarmow L, Boelskift S, et al. Differences between Nisolodiping and lisinopril on glomerular filtration rates and albuminuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment . Diabetes 1997;46(3) :481 ~ 481

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