摘要
目的 对比空斑减少中和试验与反向被动血凝抑制试验在评价人血清抗乙脑病毒抗体时测定结果的异同。方法 对 4 5 0名 6~ 10岁儿童接种灭活乙脑疫苗前后的血清样本用两种方法进行了测定。结果 两种方法在测定免前人血清抗乙脑病毒抗体时存在显著性差异 ,在测定免后人血清抗乙脑病毒抗体时两者没有差异。结论 空斑减少中和试验比反向被动血凝抑制试验在测定人血清抗乙脑病毒抗体时灵敏。
Objective In order to evaluate the difference between plaque reduction neutralization test(PRNT) and reverse passive hemagglutination inhibition(RPHI) test on human anti Japanese encephilitis antibodies.Methods Pre-and postimmunization sera collected from 450 children aged 6-10 years old after vaccination with inactivated JE were detected by both methods.Results No significant difference was found between these two methods when they were used to measure the post immunization sera,but significant differnce was found between these two methods when they were used to measure the preimmunization sera.Conclusion PRNT was more sensitive than RPHI when they were used to measure the anti Japanese Encephilitis antibodies.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2002年第3期314-315,共2页
Chinese Journal of Public Health
关键词
空斑减少中和试验
反向被动血凝抑制试验
抗乙脑病毒抗体
血清
乙脑病毒
plaque reduction neutralization test
reverse passive hemagglutination inhibition test
anti Japanese
encephilitis antibodies