氨甲苯酸预防继发性前房积血的效果观察

The effect of aminomethylbenzoic acid on preventing secondary hyphema.

目的 观察氨甲苯酸预防眼挫伤后继发性前房积血的效果。方法 92例 ( 92眼 )眼挫伤后前房积血患者 ,平均年龄 33 7± 11 72岁 ( 3～ 6 7岁 ) ,随机分为试验组 ( 6 0眼 )和对照组 ( 32眼 ) ,分别口服氨甲苯酸和维生素B1,比较两组继发性前房积血的发生率。结果 试验组继发性前房积血的发生率为 3 33% ,对照组为 34 38% ,两组间有显著性差异 (P <0 0 1)。

Objective To observe the effect of aminomethylbenzoic acid (PAMBA) preventing secondary hyphema after ocular contusion.Methods 92 cases (92 eyes) whose mean age were 33.7±11.72 years old (range 3 to 67 years old) with hyphema after ocular contusion were randomly divided into two groups,the observing group treated with PAMBA,the control group treated with placebo (Vitamin B1),then compared the occurrence rate of secondary hyphema in two groups.Results The occurrence rate of secondary hyphema was 3.33% in the observing group and 34.38% in the control group respectively (P<0.01).Conclusion PAMBA can significantly reduce the occurrence of secondary hyphema after ocular contusion.