酸枣仁汤的镇静催眠作用

Preliminary study on the sedative and hypnotic effects of the Suanzaoren Decoction

目的对酸枣仁汤镇静催眠药理作用进行初探。方法采用镇静催眠实验观察酸枣仁汤对小鼠自主活动的影响 ,协同戊巴比妥钠对小鼠的催眠作用。结果酸枣仁汤能明显减少小鼠自主活动次数 ,增加阈下剂量戊巴比妥钠致小鼠睡眠只数 ,延长阈上剂量戊巴比妥钠致小鼠睡眠时间。结论酸枣仁汤有明显的镇静、催眠作用。

Objective To make a preliminary study on the sedative and hypnotic effects of the Suanzaoren Decoction.Methods Sedative and hypnotic experiments were made to observe the effects of the Suanzaoren Decoction on the spontaneous motion and hypnosis in mice.Results The results showed that the Suanzaoren Decoction could markedly inhibit spontaneous motion, enhance the sleeping number of pentobarbital sodium (subthreshold dosage) and prolong the sleeping time of sodium pentobarbital (superthreshold dosage).Conclusions The Suanzaoren Decoction possesses obvious sedative and hypnotic effects.